PUTTING COMPUTATIONAL MODELS OF IMMUNITY TO THE TEST-AN INVITED CHALLENGE TO PREDICT B.PERTUSSIS VACCINATION RESPONSES.

Putting computational models of immunity to the test-An invited challenge to predict B.pertussis vaccination responses.

Systems vaccinology studies have been used to build computational models that predict individual vaccine responses and identify the factors contributing to differences in outcome.Comparing such models is challenging due to variability in study designs.To address this, we established a community resource to compare models predicting B.pertussis boos

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Elastic power but not driving power is the key promoter of ventilator-induced lung injury in experimental acute respiratory distress syndrome

Abstract Background We dissected total power into its primary components to resolve its relative contributions to tissue damage (VILI).We hypothesized that driving power or elastic (dynamic) power offers more precise VILI risk indicators than raw total power.The relative correlations of these three measures of power with VILI-induced histologic cha

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